A pedigree is a diagram showing the ancestral relationships and transmission of genetic traits over several generations in a family. Pedigrees are used to help detect many different genetic diseases. A pedigree can also be used to help determine the chances for a parent to produce an offspring with a specific trait. Four different traits can be identified by pedigree chart analysis: autosomal dominant, autosomal recessive, x-linked, or y-linked. Partial penetrance can be shown and calculated form pedigrees. Penetrance is the percentage expressed frequency with which individuals of a given genotype manifest at least some degree of a specific mutant phenotype associated with a trait. Inbreeding, the mating between closely related organisms of traits can clearly been seen on pedigree charts. Pedigree charts of royal families have a high degree of inbreeding, because it was customary and preferable for royalty to marry another member of royalty. Genetic councilors commonly use pedigrees to help couple determine if the parents will be able to produce healthy children.
No comments:
Post a Comment